diff --git a/README.md b/README.md
index 576970f..39d587d 100644
--- a/README.md
+++ b/README.md
@@ -202,8 +202,9 @@ Run the script with `INSTANCE_DOMAIN` and `API_TOKEN` to keep updating
 node records and parsing new incoming messages. Enable debug output with `DEBUG=1`,
 specify the connection target with `CONNECTION` (default `/dev/ttyACM0`) or set it to
 an IP address (for example `192.168.1.20:4403`) to use the Meshtastic TCP
-interface. `CONNECTION` also accepts Bluetooth device addresses (e.g.,
-`ED:4D:9E:95:CF:60`) and the script attempts a BLE connection if available. To keep
+interface. `CONNECTION` also accepts Bluetooth device addresses in MAC format (e.g.,
+`ED:4D:9E:95:CF:60`) or UUID format for macOS (e.g., `C0AEA92F-045E-9B82-C9A6-A1FD822B3A9E`)
+and the script attempts a BLE connection if available. To keep
 ingestion limited, set `ALLOWED_CHANNELS` to a comma-separated whitelist (for
 example `ALLOWED_CHANNELS="Chat,Ops"`); packets on other channels are discarded.
 Use `HIDDEN_CHANNELS` to block specific channels from the web UI even when they
diff --git a/data/mesh_ingestor/interfaces.py b/data/mesh_ingestor/interfaces.py
index 9d2f717..128611f 100644
--- a/data/mesh_ingestor/interfaces.py
+++ b/data/mesh_ingestor/interfaces.py
@@ -628,7 +628,13 @@ _DEFAULT_SERIAL_PATTERNS = (
     "/dev/cu.usbserial*",
 )
 
-_BLE_ADDRESS_RE = re.compile(r"^(?:[0-9a-fA-F]{2}:){5}[0-9a-fA-F]{2}$")
+# Support both MAC addresses (Linux/Windows) and UUIDs (macOS)
+_BLE_ADDRESS_RE = re.compile(
+    r"^(?:"
+    r"(?:[0-9a-fA-F]{2}:){5}[0-9a-fA-F]{2}|"  # MAC address format
+    r"[0-9a-fA-F]{8}-[0-9a-fA-F]{4}-[0-9a-fA-F]{4}-[0-9a-fA-F]{4}-[0-9a-fA-F]{12}"  # UUID format
+    r")$"
+)
 
 
 class _DummySerialInterface:
@@ -642,13 +648,13 @@ class _DummySerialInterface:
 
 
 def _parse_ble_target(value: str) -> str | None:
-    """Return an uppercase BLE MAC address when ``value`` matches the format.
+    """Return a normalized BLE address (MAC or UUID) when ``value`` matches the format.
 
     Parameters:
         value: User-provided target string.
 
     Returns:
-        The normalised MAC address or ``None`` when validation fails.
+        The normalised MAC address or UUID, or ``None`` when validation fails.
     """
 
     if not value:
@@ -772,10 +778,13 @@ def _create_serial_interface(port: str) -> tuple[object, str]:
         return _DummySerialInterface(), "mock"
     ble_target = _parse_ble_target(port_value)
     if ble_target:
+        # Determine if it's a MAC address or UUID
+        address_type = "MAC" if ":" in ble_target else "UUID"
         config._debug_log(
             "Using BLE interface",
             context="interfaces.ble",
             address=ble_target,
+            address_type=address_type,
         )
         return _load_ble_interface()(address=ble_target), ble_target
     network_target = _parse_network_target(port_value)
diff --git a/tests/test_mesh.py b/tests/test_mesh.py
index e7ac5bd..ad3b37d 100644
--- a/tests/test_mesh.py
+++ b/tests/test_mesh.py
@@ -2640,6 +2640,62 @@ def test_parse_ble_target_rejects_invalid_values(mesh_module):
     assert mesh._parse_ble_target("zz:zz:zz:zz:zz:zz") is None
 
 
+def test_parse_ble_target_accepts_mac_addresses(mesh_module):
+    """Test that _parse_ble_target accepts valid MAC address format (Linux/Windows)."""
+    mesh = mesh_module
+
+    # Valid MAC addresses should be accepted and normalized to uppercase
+    assert mesh._parse_ble_target("ED:4D:9E:95:CF:60") == "ED:4D:9E:95:CF:60"
+    assert mesh._parse_ble_target("ed:4d:9e:95:cf:60") == "ED:4D:9E:95:CF:60"
+    assert mesh._parse_ble_target("AA:BB:CC:DD:EE:FF") == "AA:BB:CC:DD:EE:FF"
+    assert mesh._parse_ble_target("00:11:22:33:44:55") == "00:11:22:33:44:55"
+
+    # With whitespace
+    assert mesh._parse_ble_target("  ED:4D:9E:95:CF:60  ") == "ED:4D:9E:95:CF:60"
+
+    # Invalid MAC addresses should be rejected
+    assert mesh._parse_ble_target("ED:4D:9E:95:CF") is None  # Too short
+    assert mesh._parse_ble_target("ED:4D:9E:95:CF:60:AB") is None  # Too long
+    assert mesh._parse_ble_target("GG:HH:II:JJ:KK:LL") is None  # Invalid hex
+
+
+def test_parse_ble_target_accepts_uuids(mesh_module):
+    """Test that _parse_ble_target accepts valid UUID format (macOS)."""
+    mesh = mesh_module
+
+    # Valid UUIDs should be accepted and normalized to uppercase
+    assert (
+        mesh._parse_ble_target("C0AEA92F-045E-9B82-C9A6-A1FD822B3A9E")
+        == "C0AEA92F-045E-9B82-C9A6-A1FD822B3A9E"
+    )
+    assert (
+        mesh._parse_ble_target("c0aea92f-045e-9b82-c9a6-a1fd822b3a9e")
+        == "C0AEA92F-045E-9B82-C9A6-A1FD822B3A9E"
+    )
+    assert (
+        mesh._parse_ble_target("12345678-1234-5678-9ABC-DEF012345678")
+        == "12345678-1234-5678-9ABC-DEF012345678"
+    )
+
+    # With whitespace
+    assert (
+        mesh._parse_ble_target("  C0AEA92F-045E-9B82-C9A6-A1FD822B3A9E  ")
+        == "C0AEA92F-045E-9B82-C9A6-A1FD822B3A9E"
+    )
+
+    # Invalid UUIDs should be rejected
+    assert mesh._parse_ble_target("C0AEA92F-045E-9B82-C9A6") is None  # Too short
+    assert (
+        mesh._parse_ble_target("C0AEA92F-045E-9B82-C9A6-A1FD822B3A9E-EXTRA") is None
+    )  # Too long
+    assert (
+        mesh._parse_ble_target("GGGGGGGG-GGGG-GGGG-GGGG-GGGGGGGGGGGG") is None
+    )  # Invalid hex
+    assert (
+        mesh._parse_ble_target("C0AEA92F:045E:9B82:C9A6:A1FD822B3A9E") is None
+    )  # Wrong separator
+
+
 def test_parse_network_target_additional_cases(mesh_module):
     mesh = mesh_module